Entity Details
| Primary name |
DHB2_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | P37059 |
| EntryName | DHB2_HUMAN |
| FullName | 17-beta-hydroxysteroid dehydrogenase type 2 |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 387 |
| SequenceStatus | complete |
| DateCreated | 1994-06-01 |
| DateModified | 2021-04-07 |
GO terms
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| GO | Name |
| GO:0001701 | in utero embryonic development |
| GO:0001890 | placenta development |
| GO:0004303 | estradiol 17-beta-dehydrogenase activity |
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0006703 | estrogen biosynthetic process |
| GO:0016021 | integral component of membrane |
| GO:0032526 | response to retinoic acid |
| GO:0044594 | 17-beta-hydroxysteroid dehydrogenase (NAD+) activity |
| GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity |
| GO:0047035 | testosterone dehydrogenase (NAD+) activity |
| GO:0072582 | 17-beta-hydroxysteroid dehydrogenase (NADP+) activity |
Subcellular Location
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| Subcellular Location |
| Membrane |
Domains
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| Domain | Name | Category | Type |
| IPR002347 | Short-chain dehydrogenase/reductase SDR | Family | Family |
| IPR020904 | Short-chain dehydrogenase/reductase, conserved site | Site | Conserved site |
| IPR036291 | NAD(P)-binding domain superfamily | Family | Homologous superfamily |
Drugs
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| Drug | Name | Source | Type |
| DB00157 | NADH | Drugbank | small molecule |
| DB13952 | Estradiol acetate | Drugbank | small molecule |
| DB13953 | Estradiol benzoate | Drugbank | small molecule |
| DB13954 | Estradiol cypionate | Drugbank | small molecule |
| DB13955 | Estradiol dienanthate | Drugbank | small molecule |
| DB13956 | Estradiol valerate | Drugbank | small molecule |
Interactions
0 interactions
| Interactor | Partner | Sources | Publications | Link |