Entity Details

Primary name AP4A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP50583
EntryNameAP4A_HUMAN
FullNameBis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
TaxID9606
Evidenceevidence at protein level
Length147
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesNUDT2

GO terms

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GOName
GO:0004081 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
GO:0005525 GTP binding
GO:0005759 mitochondrial matrix
GO:0006139 nucleobase-containing compound metabolic process
GO:0006167 AMP biosynthetic process
GO:0006754 ATP biosynthetic process
GO:0006915 apoptotic process
GO:0008803 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity
GO:0034599 cellular response to oxidative stress

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000086 NUDIX hydrolase domainDomainDomain
IPR003565 Bis(5'-nucleosyl)-tetraphosphataseFamilyFamily
IPR015797 NUDIX hydrolase-like domain superfamilyFamilyHomologous superfamily
IPR020084 NUDIX hydrolase, conserved siteSiteConserved site

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
AP4A_HUMANMCM6_HUMANBioGRID, IntAct25416956 details
AP4A_HUMANDDT4L_HUMANBioGRID, IntAct32296183 details
AP4A_HUMANPKHF2_HUMANBioGRID, IntAct32296183 details