Entity Details

Primary name NH2L1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP55769
EntryNameNH2L1_HUMAN
FullNameNHP2-like protein 1
TaxID9606
Evidenceevidence at protein level
Length128
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesSNU13

GO terms

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GOName
GO:0000398 mRNA splicing, via spliceosome
GO:0000470 maturation of LSU-rRNA
GO:0001651 dense fibrillar component
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005690 U4atac snRNP
GO:0005730 nucleolus
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0030621 U4 snRNA binding
GO:0030622 U4atac snRNA binding
GO:0031428 box C/D RNP complex
GO:0032040 small-subunit processome
GO:0032991 protein-containing complex
GO:0034511 U3 snoRNA binding
GO:0034512 box C/D RNA binding
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0051117 ATPase binding
GO:0071005 U2-type precatalytic spliceosome
GO:0071011 precatalytic spliceosome

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR002415 H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryoteFamilyFamily
IPR004037 Ribosomal protein L7Ae conserved siteSiteConserved site
IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45DomainDomain
IPR018492 Ribosomal protein L7Ae/L8/Nhp2 familyFamilyFamily
IPR029064 50S ribosomal protein L30e-likeFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB02494 (S)-3-phenyllactic acidDrugbanksmall molecule
DB07374 AnisomycinDrugbanksmall molecule

Interactions

26 interactions

InteractorPartnerSourcesPublicationsLink
NH2L1_HUMANCDN2C_HUMANBioGRID, HPRD, IntAct16169070 details
NH2L1_HUMANXRCC6_HUMANBioGRID, HPRD, IntAct16169070 details
NH2L1_HUMANTF3C1_HUMANBioGRID, HPRD, IntAct16169070 details
NH2L1_HUMANDPOA2_HUMANBioGRID, HPRD, IntAct16169070 details
NH2L1_HUMANRBM10_HUMANBioGRID, HPRD, IntAct16169070 details
NH2L1_HUMANCHST1_HUMANBioGRID, IntAct21988832 details
NH2L1_HUMANMLP3B_HUMANBioGRID, IntAct21988832 details
NH2L1_HUMANSNW1_HUMANBioGRID, MINT22365833 details
NH2L1_HUMANNUFP1_HUMANbhf-ucl, BioGRID17636026 24234454 25404746 27594683 details
NH2L1_HUMANPRP4_HUMANBioGRID, IntAct16723661 22863883 26344197 26496610 28514442 details
NH2L1_HUMANSMN_HUMANBioGRID, IntAct32296183 details
NH2L1_HUMANHSPB2_HUMANbhf-ucl, BioGRID26465331 details
NH2L1_HUMANPRPF3_HUMANBioGRID, IntAct16723661 28514442 details
NH2L1_HUMANLRIF1_HUMANBioGRID, HPRD16169070 details
NH2L1_HUMANRAD17_HUMANBioGRID, HPRD10593953 details
NH2L1_HUMANNH2L1_HUMANBioGRID16723661 details
NH2L1_HUMANPPIH_HUMANBioGRID16723661 details
NH2L1_HUMANPRP31_HUMANBioGRID16723661 26275778 details
NH2L1_HUMANRHOU_HUMANBioGRID26598620 details
NH2L1_HUMANRIF1_HUMANIntAct16169070 details
NH2L1_HUMANEPB41_HUMANIntAct17353931 details
NH2L1_HUMANTRAF6_HUMANIntAct17353931 details
NH2L1_HUMANNOP56_HUMANBioGRID, IntAct12777385 22939629 26344197 30021884 details
NH2L1_HUMANZNHI3_HUMANBioGRID25404746 27594683 details
NH2L1_HUMANRUVB1_HUMANBioGRID25404746 details
NH2L1_HUMANFGF11_HUMANBioGRID28027390 details