Entity Details

Primary name GABT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP80404
EntryNameGABT_HUMAN
FullName4-aminobutyrate aminotransferase, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length500
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesABAT

GO terms

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GOName
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0009448 gamma-aminobutyric acid metabolic process
GO:0009450 gamma-aminobutyric acid catabolic process
GO:0030170 pyridoxal phosphate binding
GO:0032144 4-aminobutyrate transaminase complex
GO:0032145 succinate-semialdehyde dehydrogenase binding
GO:0034386 4-aminobutyrate:2-oxoglutarate transaminase activity
GO:0042135 neurotransmitter catabolic process
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0047298 (S)-3-amino-2-methylpropionate transaminase activity
GO:0048148 behavioral response to cocaine
GO:0051536 iron-sulfur cluster binding

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR004631 4-aminobutyrate aminotransferase, eukaryoticFamilyFamily
IPR005814 Aminotransferase class-IIIFamilyFamily
IPR015421 Pyridoxal phosphate-dependent transferase, major domainFamilyHomologous superfamily
IPR015422 Pyridoxal phosphate-dependent transferase, small domainFamilyHomologous superfamily
IPR015424 Pyridoxal phosphate-dependent transferaseFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00114 Pyridoxal phosphateDrugbanksmall molecule
DB00119 Pyruvic acidDrugbanksmall molecule
DB00142 Glutamic acidDrugbanksmall molecule
DB00160 AlanineDrugbanksmall molecule
DB00780 PhenelzineDrugbanksmall molecule
DB01080 VigabatrinDrugbanksmall molecule
DB01699 (4e)-4-Aminohex-4-Enoic AcidDrugbanksmall molecule
DB04235 4-Amino Hexanoic AcidDrugbanksmall molecule

Interactions

3 interactions