Entity Details

Primary name CAC1B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ00975
EntryNameCAC1B_HUMAN
FullNameVoltage-dependent N-type calcium channel subunit alpha-1B
TaxID9606
Evidenceevidence at protein level
Length2339
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCACNA1B

GO terms

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GOName
GO:0001540 amyloid-beta binding
GO:0005245 voltage-gated calcium channel activity
GO:0005509 calcium ion binding
GO:0005524 ATP binding
GO:0005886 plasma membrane
GO:0005891 voltage-gated calcium channel complex
GO:0006816 calcium ion transport
GO:0007268 chemical synaptic transmission
GO:0008022 protein C-terminus binding
GO:0008331 high voltage-gated calcium channel activity
GO:0034765 regulation of ion transmembrane transport
GO:0045202 synapse
GO:0050804 modulation of chemical synaptic transmission
GO:0051899 membrane depolarization
GO:0070509 calcium ion import
GO:1904645 response to amyloid-beta

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR002048 EF-hand domainDomainDomain
IPR002077 Voltage-dependent calcium channel, alpha-1 subunitFamilyFamily
IPR005447 Voltage-dependent calcium channel, N-type, alpha-1 subunitFamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR014873 Voltage-dependent calcium channel, alpha-1 subunit, IQ domainDomainDomain
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR031649 Voltage-dependent L-type calcium channel, IQ-associated domainDomainDomain
IPR043203 Voltage-gated cation channel calcium and sodiumFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00153 ErgocalciferolDrugbanksmall molecule
DB00228 EnfluraneDrugbanksmall molecule
DB00381 AmlodipineDrugbanksmall molecule
DB00421 SpironolactoneDrugbanksmall molecule
DB00661 VerapamilDrugbanksmall molecule
DB00996 GabapentinDrugbanksmall molecule
DB01202 LevetiracetamDrugbanksmall molecule
DB05885 SeletracetamDrugbanksmall molecule
DB05950 Contulakin-GDrugbanksmall molecule
DB06283 ZiconotideDrugbanksmall molecule
DB08838 AgmatineDrugbanksmall molecule
DB09231 BenidipineDrugbanksmall molecule
DB09232 CilnidipineDrugbanksmall molecule
DB11148 ButambenDrugbanksmall molecule
DB13746 BioallethrinDrugbanksmall molecule