Entity Details

Primary name PFKAP_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ01813
EntryNamePFKAP_HUMAN
FullNameATP-dependent 6-phosphofructokinase, platelet type
TaxID9606
Evidenceevidence at protein level
Length784
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesPFKP

GO terms

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GOName
GO:0003872 6-phosphofructokinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005945 6-phosphofructokinase complex
GO:0006002 fructose 6-phosphate metabolic process
GO:0016020 membrane
GO:0016208 AMP binding
GO:0030388 fructose 1,6-bisphosphate metabolic process
GO:0042802 identical protein binding
GO:0044877 protein-containing complex binding
GO:0045296 cadherin binding
GO:0046872 metal ion binding
GO:0048029 monosaccharide binding
GO:0061621 canonical glycolysis
GO:0070062 extracellular exosome
GO:0070095 fructose-6-phosphate binding
GO:1990830 cellular response to leukemia inhibitory factor

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000023 Phosphofructokinase domainDomainDomain
IPR009161 ATP-dependent 6-phosphofructokinase, eukaryotic-typeFamilyFamily
IPR015912 Phosphofructokinase, conserved siteSiteConserved site
IPR022953 ATP-dependent 6-phosphofructokinaseFamilyFamily
IPR035966 Phosphofructokinase superfamilyFamilyHomologous superfamily
IPR041914 ATP-dependent 6-phosphofructokinase, vertebrate-typeFamilyFamily

Diseases

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Interactions

35 interactions

InteractorPartnerSourcesPublicationsLink
PFKAP_HUMANAGO2_HUMANBioGRID, IntAct21988832 details
PFKAP_HUMANWNK1_HUMANBioGRID, IntAct21988832 details
PFKAP_HUMANTERF1_HUMANbhf-ucl, BioGRID21044950 details
PFKAP_HUMANTINF2_HUMANbhf-ucl, BioGRID21044950 details
PFKAP_HUMANACD_HUMANbhf-ucl, BioGRID21044950 details
PFKAP_HUMANPOTE1_HUMANbhf-ucl, BioGRID21044950 details
PFKAP_HUMANNTF2_HUMANBioGRID, IntAct32296183 details
PFKAP_HUMANPFKAP_HUMANDIP25985179 details
PFKAP_HUMANEGFR_HUMANBioGRID23956138 24797263 29677490 details
PFKAP_HUMANAKT1_HUMANBioGRID29038421 details
PFKAP_HUMANRO52_HUMANBioGRID29038421 details
PFKAP_HUMANKAT5_HUMANBioGRID29677490 details
PFKAP_HUMANP85A_HUMANBioGRID29677490 details
PFKAP_HUMANSUMO2_HUMANBioGRID32786267 details
PFKAP_HUMANTNR1B_HUMANIntAct14743216 details
PFKAP_HUMANARF6_HUMANIntAct17353931 details
PFKAP_HUMANGBRL2_HUMANIntAct17353931 details
PFKAP_HUMANGSTK1_HUMANIntAct17353931 details
PFKAP_HUMANBCAR3_HUMANIntAct17353931 details
PFKAP_HUMANHLAB_HUMANIntAct17353931 details
PFKAP_HUMANAAKB1_HUMANIntAct17353931 details
PFKAP_HUMANTRAF6_HUMANIntAct17353931 details
PFKAP_HUMAN1433Z_HUMANMINT15161933 details
PFKAP_HUMANMAX_HUMANIntAct20195357 details
PFKAP_HUMANIF122_HUMANBioGRID, IntAct27173435 unassigned1312 details
PFKAP_HUMANWDR19_HUMANBioGRID, IntAct27173435 unassigned1312 details
PFKAP_HUMANPFKAM_HUMANBioGRID, IntAct22863883 22939629 28514442 29038421 details
PFKAP_HUMANPARD3_HUMANBioGRID18685789 details
PFKAP_HUMANITA4_HUMANBioGRID22623428 details
PFKAP_HUMANRN126_HUMANBioGRID26508657 details
PFKAP_HUMANMCM9_HUMANBioGRID26300262 26870752 details
PFKAP_HUMANAKT2_HUMANBioGRID29038421 details
PFKAP_HUMANAKT3_HUMANBioGRID29038421 details
PFKAP_HUMANGAB1_HUMANBioGRID29677490 details
PFKAP_HUMANDYL1_HUMANHPRD14760703 details