Entity Details

Primary name CLIC2
Entity type gene
Source Source Link

Details

PrimaryID1193
RefseqGeneNG_012497
SymbolCLIC2
Namechloride intracellular channel 2
ChromosomeX
LocationXq28
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-17
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCLIC2_HUMAN

GO terms

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GOName
GO:0004602 glutathione peroxidase activity
GO:0005244 voltage-gated ion channel activity
GO:0005254 chloride channel activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006749 glutathione metabolic process
GO:0007165 signal transduction
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0034707 chloride channel complex
GO:0051099 positive regulation of binding
GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity
GO:1902476 chloride transmembrane transport

Diseases

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Interactions

8 interactions

InteractorPartnerSourcesPublicationsLink
CLIC2TPRNBioGRID, IntAct32296183 details
CLIC2TRAPPC2BioGRID, HPRD12681486 details
CLIC2NEDD4BioGRID19953087 details
CLIC2NEDD4LBioGRID19953087 details
CLIC2FN1BioGRID, IntAct19738201 details
CLIC2CLIC4BioGRID, IntAct26186194 28514442 details
CLIC2CLIC5BioGRID, IntAct26186194 28514442 details
CLIC2KIF14BioGRID31586073 details