Entity Details

Primary name DAO
Entity type gene
Source Source Link

Details

PrimaryID1610
RefseqGeneNG_023236
SymbolDAO
NameD-amino acid oxidase
Chromosome12
Location12q24.11
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-06
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsOXDA_HUMAN

GO terms

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GOName
GO:0003884 D-amino-acid oxidase activity
GO:0005737 cytoplasm
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0005782 peroxisomal matrix
GO:0005829 cytosol
GO:0006562 proline catabolic process
GO:0008104 protein localization
GO:0019478 D-amino acid catabolic process
GO:0019752 carboxylic acid metabolic process
GO:0036088 D-serine catabolic process
GO:0042416 dopamine biosynthetic process
GO:0042802 identical protein binding
GO:0055130 D-alanine catabolic process
GO:0070178 D-serine metabolic process
GO:0071949 FAD binding

Diseases

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Disease IDSourceNameDescription
181500 OMIMSchizophrenia (SCZD)A complex, multifactorial psychotic disorder or group of disorders characterized by disturbances in the form and content of thought (e.g. delusions, hallucinations), in mood (e.g. inappropriate affect), in sense of self and relationship to the external world (e.g. loss of ego boundaries, withdrawal), and in behavior (e.g bizarre or apparently purposeless behavior). Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. Some patients manifest schizophrenic as well as bipolar disorder symptoms and are often given the diagnosis of schizoaffective disorder. Disease susceptibility may be associated with variants affecting the gene represented in this entry.

Interactions

9 interactions

InteractorPartnerSourcesPublicationsLink
DAOEP300BioGRID, IntAct21988832 details
DAOPRKAB2BioGRID, IntAct21988832 24722188 25416956 31515488 details
DAOPEX5BioGRID20178365 details
DAODAOABioGRID, HPRD12364586 18544534 details
DAODAOBioGRID18544534 details
DAOAOC1HPRD8195119 details
DAOKLHL42BioGRID, IntAct28514442 details
DAOGSTM1BioGRID, IntAct28514442 details
DAONME2BioGRID28514442 details