Entity Details

Primary name DECR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ16698
EntryNameDECR_HUMAN
FullName2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial
TaxID9606
Evidenceevidence at protein level
Length335
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesDECR1

GO terms

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GOName
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0006635 fatty acid beta-oxidation
GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity
GO:0042802 identical protein binding
GO:0070402 NADPH binding
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1902494 catalytic complex

Subcellular Location

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Subcellular Location
Mitochondrion

Domains

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DomainNameCategoryType
IPR002347 Short-chain dehydrogenase/reductase SDRFamilyFamily
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB03461 Nicotinamide adenine dinucleotide phosphateDrugbanksmall molecule
DB08605 6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OLDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
DECR_HUMANHGS_HUMANBioGRID19019082 details
DECR_HUMANA4_HUMANBioGRID21832049 details
DECR_HUMANITA4_HUMANBioGRID22623428 details