Entity Details

Primary name SFTPA2
Entity type gene
Source Source Link

Details

PrimaryID729238
RefseqGeneNG_013046
SymbolSFTPA2
Namesurfactant protein A2
Chromosome10
Location10q22.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2006-07-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSFPA2_HUMAN

GO terms

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GOName
GO:0002224 toll-like receptor signaling pathway
GO:0005576 extracellular region
GO:0005581 collagen trimer
GO:0005615 extracellular space
GO:0005771 multivesicular body
GO:0005789 endoplasmic reticulum membrane
GO:0005791 rough endoplasmic reticulum
GO:0007585 respiratory gaseous exchange by respiratory system
GO:0030246 carbohydrate binding
GO:0042599 lamellar body
GO:0044267 cellular protein metabolic process
GO:0045334 clathrin-coated endocytic vesicle

Diseases

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Disease IDSourceNameDescription
178500 OMIMPulmonary fibrosis, idiopathic (IPF)A lung disease characterized by shortness of breath, radiographically evident diffuse pulmonary infiltrates, and varying degrees of inflammation and fibrosis on biopsy. In some cases, the disorder can be rapidly progressive and characterized by sequential acute lung injury with subsequent scarring and end-stage lung disease. The disease is caused by variants affecting the gene represented in this entry.

Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
SFTPA2NCS1BioGRID, IntAct32296183 details
SFTPA2UBQLN2BioGRID, IntAct32296183 details
SFTPA2CORO1BBioGRID26344197 details
SFTPA2CORO1CBioGRID26344197 details
SFTPA2NR3C1BioGRID31182584 details