Entity Details

Primary name STEA4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ687X5
EntryNameSTEA4_HUMAN
FullNameMetalloreductase STEAP4
TaxID9606
Evidenceevidence at protein level
Length459
SequenceStatuscomplete
DateCreated2007-05-01
DateModified2021-06-02

Ontological Relatives

GenesSTEAP4

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0005654 nucleoplasm
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0008823 cupric reductase activity
GO:0009055 electron transfer activity
GO:0015677 copper ion import
GO:0016021 integral component of membrane
GO:0020037 heme binding
GO:0031901 early endosome membrane
GO:0033212 iron import into cell
GO:0045444 fat cell differentiation
GO:0046872 metal ion binding
GO:0052851 ferric-chelate reductase (NADPH) activity
GO:0070062 extracellular exosome
GO:0070207 protein homotrimerization
GO:0071949 FAD binding

Subcellular Location

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Subcellular Location
Cell membrane
Early endosome membrane
Golgi apparatus membrane

Domains

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DomainNameCategoryType
IPR013130 Ferric reductase transmembrane component-like domainDomainDomain
IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminalDomainDomain
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
STEA4_HUMANAKT2_HUMANBioGRID, IntAct21988832 details
STEA4_HUMANTERT_HUMANBioGRID23741361 details