Entity Details

Primary name TWF2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6IBS0
EntryNameTWF2_HUMAN
FullNameTwinfilin-2
TaxID9606
Evidenceevidence at protein level
Length349
SequenceStatuscomplete
DateCreated2006-05-02
DateModified2021-06-02

Ontological Relatives

GenesTWF2

GO terms

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GOName
GO:0003723 RNA binding
GO:0003785 actin monomer binding
GO:0005080 protein kinase C binding
GO:0005524 ATP binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 cytoplasm
GO:0005884 actin filament
GO:0010591 regulation of lamellipodium assembly
GO:0010592 positive regulation of lamellipodium assembly
GO:0010976 positive regulation of neuron projection development
GO:0030016 myofibril
GO:0030027 lamellipodium
GO:0030030 cell projection organization
GO:0030042 actin filament depolymerization
GO:0030175 filopodium
GO:0030426 growth cone
GO:0030837 negative regulation of actin filament polymerization
GO:0032420 stereocilium
GO:0032532 regulation of microvillus length
GO:0032956 regulation of actin cytoskeleton organization
GO:0042989 sequestering of actin monomers
GO:0045296 cadherin binding
GO:0045773 positive regulation of axon extension
GO:0048471 perinuclear region of cytoplasm
GO:0051015 actin filament binding
GO:0051016 barbed-end actin filament capping
GO:0070062 extracellular exosome
GO:0071300 cellular response to retinoic acid
GO:0071363 cellular response to growth factor stimulus

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR002108 Actin-depolymerising factor homology domainDomainDomain
IPR028458 TwinfilinFamilyFamily
IPR029006 ADF-H/Gelsolin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

7 interactions