Entity Details

Primary name GDF6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6KF10
EntryNameGDF6_HUMAN
FullNameGrowth/differentiation factor 6
TaxID9606
Evidenceevidence at protein level
Length455
SequenceStatuscomplete
DateCreated2005-10-11
DateModified2021-06-02

Ontological Relatives

GenesGDF6

GO terms

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GOName
GO:0001656 metanephros development
GO:0005125 cytokine activity
GO:0005615 extracellular space
GO:0006915 apoptotic process
GO:0008083 growth factor activity
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0030509 BMP signaling pathway
GO:0032332 positive regulation of chondrocyte differentiation
GO:0032924 activin receptor signaling pathway
GO:0045444 fat cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0060389 pathway-restricted SMAD protein phosphorylation
GO:0060395 SMAD protein signal transduction
GO:1900745 positive regulation of p38MAPK cascade
GO:1990009 retinal cell apoptotic process

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001111 TGF-beta, propeptideDomainDomain
IPR001839 Transforming growth factor-beta, C-terminalDomainDomain
IPR015615 Transforming growth factor-beta-relatedFamilyFamily
IPR017948 Transforming growth factor beta, conserved siteSiteConserved site
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

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Interactions

5 interactions