Entity Details

Primary name ATAD2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6PL18
EntryNameATAD2_HUMAN
FullNameATPase family AAA domain-containing protein 2
TaxID9606
Evidenceevidence at protein level
Length1390
SequenceStatuscomplete
DateCreated2005-09-13
DateModified2021-06-02

Ontological Relatives

GenesATAD2

GO terms

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GOName
GO:0003682 chromatin binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006325 chromatin organization
GO:0006357 regulation of transcription by RNA polymerase II
GO:0016887 ATP hydrolysis activity
GO:0031936 negative regulation of chromatin silencing
GO:0042393 histone binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001487 BromodomainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR003959 ATPase, AAA-type, coreDomainDomain
IPR003960 ATPase, AAA-type, conserved siteSiteConserved site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR031252 ATPase family AAA domain-containing protein 2FamilyFamily
IPR036427 Bromodomain-like superfamilyFamilyHomologous superfamily
IPR041569 AAA ATPase, AAA+ lid domainDomainDomain

Diseases

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