Entity Details

Primary name MAEA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ7L5Y9
EntryNameMAEA_HUMAN
FullNameE3 ubiquitin-protein transferase MAEA
TaxID9606
Evidenceevidence at protein level
Length396
SequenceStatuscomplete
DateCreated2007-05-01
DateModified2021-06-02

Ontological Relatives

GenesMAEA

GO terms

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GOName
GO:0000151 ubiquitin ligase complex
GO:0003779 actin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005826 actomyosin contractile ring
GO:0005856 cytoskeleton
GO:0005887 integral component of plasma membrane
GO:0007049 cell cycle
GO:0007155 cell adhesion
GO:0007346 regulation of mitotic cell cycle
GO:0016363 nuclear matrix
GO:0033033 negative regulation of myeloid cell apoptotic process
GO:0034657 GID complex
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043249 erythrocyte maturation
GO:0045721 negative regulation of gluconeogenesis
GO:0046872 metal ion binding
GO:0051301 cell division
GO:0061630 ubiquitin protein ligase activity

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Nucleus
Nucleus matrix

Domains

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DomainNameCategoryType
IPR006594 LIS1 homology motifDomainDomain
IPR006595 CTLH, C-terminal LisH motifDomainDomain
IPR013144 CRA domainDomainDomain
IPR024964 CTLH/CRA C-terminal to LisH motif domainDomainDomain
IPR027714 Protein Fyv10/E3 ubiquitin-protein transferase MAEAFamilyFamily
IPR044063 Gid-type RING finger domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB05389 TetrachlorodecaoxideDrugbanksmall molecule

Interactions

25 interactions

InteractorPartnerSourcesPublicationsLink
MAEA_HUMANARMC8_HUMANBioGRID, IntAct27173435 29911972 unassigned1312 details
MAEA_HUMANGID8_HUMANBioGRID, IntAct17467196 27173435 29911972 unassigned1312 details
MAEA_HUMANMKLN1_HUMANBioGRID, IntAct17467196 27173435 29911972 unassigned1312 details
MAEA_HUMANWDR26_HUMANBioGRID, IntAct27173435 29911972 31285494 unassigned1312 details
MAEA_HUMANRBP10_HUMANBioGRID, IntAct27173435 29911972 unassigned1312 details
MAEA_HUMANGID4_HUMANBioGRID, IntAct27173435 29911972 unassigned1312 details
MAEA_HUMANRANB9_HUMANBioGRID, IntAct17467196 26344197 27173435 29911972 30795516 31285494 unassigned1312 details
MAEA_HUMANYPEL5_HUMANBioGRID, IntAct24981860 27173435 29911972 unassigned1312 details
MAEA_HUMANRMD5A_HUMANBioGRID, IntAct17467196 26186194 27173435 28514442 29911972 unassigned1312 details
MAEA_HUMANGSK3A_HUMANBioGRID, UniProt30824926 details
MAEA_HUMANMYOC_HUMANBioGRID, HPRD16289162 details
MAEA_HUMANUBE2H_HUMANBioGRID29911972 details
MAEA_HUMANUB2R2_HUMANBioGRID29911972 details
MAEA_HUMANUB2D3_HUMANBioGRID29911972 details
MAEA_HUMANMAEA_HUMANBioGRID31285494 details
MAEA_HUMANEFHC2_HUMANBioGRID, IntAct27173435 unassigned1312 details
MAEA_HUMANRMD5B_HUMANBioGRID, IntAct27173435 unassigned1312 details
MAEA_HUMANDDX5_HUMANBioGRID, IntAct27173435 unassigned1312 details
MAEA_HUMANHTRA2_HUMANBioGRID, IntAct27173435 unassigned1312 details
MAEA_HUMANMITOK_HUMANBioGRID, IntAct27173435 unassigned1312 details
MAEA_HUMANRAB8A_HUMANBioGRID, IntAct27173435 unassigned1312 details
MAEA_HUMANFMR1_HUMANIntAct31413325 details
MAEA_HUMANHBP1_HUMANBioGRID29911972 details
MAEA_HUMANRAF1_HUMANBioGRID30795516 details
MAEA_HUMANTULP3_HUMANBioGRID33187986 details