Entity Details

Primary name FRMD5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ7Z6J6
EntryNameFRMD5_HUMAN
FullNameFERM domain-containing protein 5
TaxID9606
Evidenceevidence at protein level
Length570
SequenceStatuscomplete
DateCreated2006-07-25
DateModified2021-06-02

Ontological Relatives

GenesFRMD5

GO terms

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GOName
GO:0005178 integrin binding
GO:0005856 cytoskeleton
GO:0005912 adherens junction
GO:0008092 cytoskeletal protein binding
GO:0016021 integral component of membrane
GO:0019901 protein kinase binding
GO:0030334 regulation of cell migration
GO:0031032 actomyosin structure organization
GO:0045785 positive regulation of cell adhesion
GO:2000146 negative regulation of cell motility

Subcellular Location

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Subcellular Location
Cell junction
Membrane

Domains

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DomainNameCategoryType
IPR000299 FERM domainDomainDomain
IPR000798 Ezrin/radixin/moesin-likeFamilyFamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR014352 FERM/acyl-CoA-binding protein superfamilyFamilyHomologous superfamily
IPR014847 FERM adjacent (FA)DomainDomain
IPR018979 FERM, N-terminalDomainDomain
IPR018980 FERM, C-terminal PH-like domainDomainDomain
IPR019747 FERM conserved siteSiteConserved site
IPR019748 FERM central domainDomainDomain
IPR019749 Band 4.1 domainDomainDomain
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR035963 FERM superfamily, second domainFamilyHomologous superfamily

Diseases

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