Entity Details

Primary name AACS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86V21
EntryNameAACS_HUMAN
FullNameAcetoacetyl-CoA synthetase
TaxID9606
Evidenceevidence at protein level
Length672
SequenceStatuscomplete
DateCreated2008-01-15
DateModified2021-06-02

Ontological Relatives

GenesAACS

GO terms

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GOName
GO:0001889 liver development
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0006631 fatty acid metabolic process
GO:0007584 response to nutrient
GO:0014074 response to purine-containing compound
GO:0030729 acetoacetate-CoA ligase activity
GO:0032024 positive regulation of insulin secretion
GO:0034201 response to oleic acid
GO:0042493 response to drug
GO:0042594 response to starvation
GO:0045471 response to ethanol
GO:0046951 ketone body biosynthetic process
GO:0047760 butyrate-CoA ligase activity
GO:0050872 white fat cell differentiation
GO:0060612 adipose tissue development
GO:0071333 cellular response to glucose stimulus
GO:0071394 cellular response to testosterone stimulus
GO:0071397 cellular response to cholesterol

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000873 AMP-dependent synthetase/ligaseDomainDomain
IPR005914 Acetoacetyl-CoA synthaseFamilyFamily
IPR020845 AMP-binding, conserved siteSiteConserved site
IPR032387 Acetyl-coenzyme A synthetase, N-terminal domainDomainDomain
IPR042099 ANL, N-terminal domainFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
AACS_HUMANCKLF5_HUMANBioGRID, IntAct25416956 details