Entity Details

Primary name SMC5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IY18
EntryNameSMC5_HUMAN
FullNameStructural maintenance of chromosomes protein 5
TaxID9606
Evidenceevidence at protein level
Length1101
SequenceStatuscomplete
DateCreated2007-01-09
DateModified2021-06-02

Ontological Relatives

GenesSMC5

GO terms

Show/Hide Table
GOName
GO:0000722 telomere maintenance via recombination
GO:0000724 double-strand break repair via homologous recombination
GO:0000775 chromosome, centromeric region
GO:0000781 chromosome, telomeric region
GO:0000803 sex chromosome
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006974 cellular response to DNA damage stimulus
GO:0007062 sister chromatid cohesion
GO:0016605 PML body
GO:0016607 nuclear speck
GO:0016887 ATP hydrolysis activity
GO:0018393 internal peptidyl-lysine acetylation
GO:0019827 stem cell population maintenance
GO:0030054 cell junction
GO:0030261 chromosome condensation
GO:0030915 Smc5-Smc6 complex
GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion
GO:0035061 interchromatin granule
GO:0035861 site of double-strand break
GO:0044772 mitotic cell cycle phase transition
GO:0051301 cell division
GO:0051984 positive regulation of chromosome segregation
GO:0071459 protein localization to chromosome, centromeric region
GO:0090398 cellular senescence

Subcellular Location

Show/Hide Table
Subcellular Location
Chromosome
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR003395 RecF/RecN/SMC, N-terminalDomainDomain
IPR027131 Structural maintenance of chromosomes protein 5FamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

Show/Hide Table