Entity Details

Primary name DOCK4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8N1I0
EntryNameDOCK4_HUMAN
FullNameDedicator of cytokinesis protein 4
TaxID9606
Evidenceevidence at protein level
Length1966
SequenceStatuscomplete
DateCreated2003-07-03
DateModified2021-06-02

Ontological Relatives

GenesDOCK4

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005096 GTPase activator activity
GO:0005730 nucleolus
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007264 small GTPase mediated signal transduction
GO:0016020 membrane
GO:0017124 SH3 domain binding
GO:0030165 PDZ domain binding
GO:0030971 receptor tyrosine kinase binding
GO:0031267 small GTPase binding
GO:0032420 stereocilium
GO:0032421 stereocilium bundle
GO:0043547 positive regulation of GTPase activity
GO:0060326 cell chemotaxis
GO:1904694 negative regulation of vascular associated smooth muscle contraction
GO:1904754 positive regulation of vascular associated smooth muscle cell migration

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR026791 Dedicator of cytokinesisFamilyFamily
IPR027007 C2 DOCK-type domainDomainDomain
IPR027357 DOCKER domainDomainDomain
IPR032376 Dedicator of cytokinesis, N-terminal domainDomainDomain
IPR035769 Dedicator of cytokinesis 4, SH3 domainDomainDomain
IPR035892 C2 domain superfamilyFamilyHomologous superfamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR037014 Dedicator of cytokinesis 4FamilyFamily
IPR037811 Dedicator of cytokinesis B, C2 domainDomainDomain
IPR042455 Dedicator of cytokinesis, N-terminal, subdomain 1FamilyHomologous superfamily
IPR043161 Dedicator of cytokinesis, C-terminal, lobe AFamilyHomologous superfamily
IPR043162 Dedicator of cytokinesis, C-terminal, lobe CFamilyHomologous superfamily

Diseases

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