Entity Details

Primary name MEIS1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00470
EntryNameMEIS1_HUMAN
FullNameHomeobox protein Meis1
TaxID9606
Evidenceevidence at protein level
Length390
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesMEIS1

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001525 angiogenesis
GO:0001654 eye development
GO:0002089 lens morphogenesis in camera-type eye
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007420 brain development
GO:0007626 locomotory behavior
GO:0008284 positive regulation of cell population proliferation
GO:0009880 embryonic pattern specification
GO:0009887 animal organ morphogenesis
GO:0030097 hemopoiesis
GO:0035855 megakaryocyte development
GO:0045638 negative regulation of myeloid cell differentiation
GO:0045665 negative regulation of neuron differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0060044 negative regulation of cardiac muscle cell proliferation
GO:0060216 definitive hemopoiesis

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR008422 Homeobox KN domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR032453 Homeobox protein PKNOX/Meis, N-terminalDomainDomain

Diseases

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