Entity Details

Primary name NMD3A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TCU5
EntryNameNMD3A_HUMAN
FullNameGlutamate receptor ionotropic, NMDA 3A
TaxID9606
Evidenceevidence at protein level
Length1115
SequenceStatuscomplete
DateCreated2004-08-31
DateModified2021-06-02

Ontological Relatives

GenesGRIN3A

GO terms

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GOName
GO:0004972 NMDA glutamate receptor activity
GO:0005262 calcium channel activity
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0006816 calcium ion transport
GO:0014069 postsynaptic density
GO:0015276 ligand-gated ion channel activity
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016358 dendrite development
GO:0016594 glycine binding
GO:0017146 NMDA selective glutamate receptor complex
GO:0035235 ionotropic glutamate receptor signaling pathway
GO:0038023 signaling receptor activity
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0045471 response to ethanol
GO:0051721 protein phosphatase 2A binding
GO:0060134 prepulse inhibition
GO:0061000 negative regulation of dendritic spine development
GO:0098978 glutamatergic synapse
GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
GO:2000300 regulation of synaptic vesicle exocytosis

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR001320 Ionotropic glutamate receptorDomainDomain
IPR001508 Ionotropic glutamate receptor, metazoaFamilyFamily
IPR019594 Ionotropic glutamate receptor, L-glutamate and glycine-binding domainDomainDomain
IPR028082 Periplasmic binding protein-like IFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00142 Glutamic acidDrugbanksmall molecule
DB00193 TramadolDrugbanksmall molecule
DB00228 EnfluraneDrugbanksmall molecule
DB00289 AtomoxetineDrugbanksmall molecule
DB00312 PentobarbitalDrugbanksmall molecule
DB00333 MethadoneDrugbanksmall molecule
DB00392 ProfenamineDrugbanksmall molecule
DB00418 SecobarbitalDrugbanksmall molecule
DB00514 DextromethorphanDrugbanksmall molecule
DB00659 AcamprosateDrugbanksmall molecule
DB00721 ProcaineDrugbanksmall molecule
DB00843 DonepezilDrugbanksmall molecule
DB00874 GuaifenesinDrugbanksmall molecule
DB00898 EthanolDrugbanksmall molecule
DB00915 AmantadineDrugbanksmall molecule
DB01043 MemantineDrugbanksmall molecule
DB01159 HalothaneDrugbanksmall molecule
DB01173 OrphenadrineDrugbanksmall molecule
DB01174 PhenobarbitalDrugbanksmall molecule
DB01221 KetamineDrugbanksmall molecule
DB01238 AripiprazoleDrugbanksmall molecule
DB01520 TenocyclidineDrugbanksmall molecule
DB01549 RolicyclidineDrugbanksmall molecule
DB01708 PrasteroneDrugbanksmall molecule
DB03575 PhencyclidineDrugbanksmall molecule
DB04896 MilnacipranDrugbanksmall molecule
DB04926 NeramexaneDrugbanksmall molecule
DB06151 AcetylcysteineDrugbanksmall molecule
DB06738 KetobemidoneDrugbanksmall molecule
DB06741 GavestinelDrugbanksmall molecule
DB09409 Magnesium acetate tetrahydrateDrugbanksmall molecule
DB09481 Magnesium carbonateDrugbanksmall molecule
DB11823 EsketamineDrugbanksmall molecule
DB13146 Fluciclovine (18F)Drugbanksmall molecule