Entity Details

Primary name HAVR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TDQ0
EntryNameHAVR2_HUMAN
FullNameHepatitis A virus cellular receptor 2
TaxID9606
Evidenceevidence at protein level
Length301
SequenceStatuscomplete
DateCreated2005-09-27
DateModified2021-06-02

Ontological Relatives

GenesHAVCR2

GO terms

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GOName
GO:0001772 immunological synapse
GO:0002250 adaptive immune response
GO:0002281 macrophage activation involved in immune response
GO:0002519 natural killer cell tolerance induction
GO:0002652 regulation of tolerance induction dependent upon immune response
GO:0002826 negative regulation of T-helper 1 type immune response
GO:0002859 negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0005769 early endosome
GO:0006954 inflammatory response
GO:0009986 cell surface
GO:0010629 negative regulation of gene expression
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030886 negative regulation of myeloid dendritic cell activation
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032687 negative regulation of interferon-alpha production
GO:0032689 negative regulation of interferon-gamma production
GO:0032703 negative regulation of interleukin-2 production
GO:0032712 negative regulation of interleukin-3 production
GO:0032715 negative regulation of interleukin-6 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032722 positive regulation of chemokine production
GO:0032729 positive regulation of interferon-gamma production
GO:0032732 positive regulation of interleukin-1 production
GO:0032753 positive regulation of interleukin-4 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0032815 negative regulation of natural killer cell activation
GO:0034138 toll-like receptor 3 signaling pathway
GO:0034154 toll-like receptor 7 signaling pathway
GO:0034162 toll-like receptor 9 signaling pathway
GO:0042102 positive regulation of T cell proliferation
GO:0042130 negative regulation of T cell proliferation
GO:0043032 positive regulation of macrophage activation
GO:0045087 innate immune response
GO:0045089 positive regulation of innate immune response
GO:0046872 metal ion binding
GO:0050830 defense response to Gram-positive bacterium
GO:0060135 maternal process involved in female pregnancy
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071222 cellular response to lipopolysaccharide
GO:0071656 negative regulation of granulocyte colony-stimulating factor production
GO:1900425 negative regulation of defense response to bacterium
GO:1900426 positive regulation of defense response to bacterium
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:2000521 negative regulation of immunological synapse formation
GO:2001189 negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Membrane

Domains

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DomainNameCategoryType
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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