Entity Details

Primary name SSH1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8WYL5
EntryNameSSH1_HUMAN
FullNameProtein phosphatase Slingshot homolog 1
TaxID9606
Evidenceevidence at protein level
Length1049
SequenceStatuscomplete
DateCreated2005-11-22
DateModified2021-06-02

Ontological Relatives

GenesSSH1

GO terms

Show/Hide Table
GOName
GO:0000902 cell morphogenesis
GO:0003779 actin binding
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0006470 protein dephosphorylation
GO:0008138 protein tyrosine/serine/threonine phosphatase activity
GO:0030027 lamellipodium
GO:0030036 actin cytoskeleton organization
GO:0030426 growth cone
GO:0030496 midbody
GO:0030837 negative regulation of actin filament polymerization
GO:0031915 positive regulation of synaptic plasticity
GO:0032154 cleavage furrow
GO:0032268 regulation of cellular protein metabolic process
GO:0045202 synapse
GO:0071318 cellular response to ATP
GO:0098976 excitatory chemical synaptic transmission
GO:0106306 protein serine phosphatase activity
GO:0106307 protein threonine phosphatase activity
GO:1901216 positive regulation of neuron death
GO:1904719 positive regulation of AMPA glutamate receptor clustering
GO:1904754 positive regulation of vascular associated smooth muscle cell migration
GO:2000463 positive regulation of excitatory postsynaptic potential

Subcellular Location

Show/Hide Table
Subcellular Location
Cell projection
Cleavage furrow
Cytoplasm
Midbody

Domains

Show/Hide Table
DomainNameCategoryType
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR014876 DEK, C-terminalDomainDomain
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR020422 Dual specificity protein phosphatase domainDomainDomain
IPR027233 Protein phosphatase Slingshot homologue 1FamilyFamily
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily
IPR043587 Protein phosphatase Slingshot-likeFamilyFamily
IPR043588 Slingshot, N-terminalDomainDomain

Diseases

Show/Hide Table