Entity Details

Primary name GBF1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92538
EntryNameGBF1_HUMAN
FullNameGolgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
TaxID9606
Evidenceevidence at protein level
Length1859
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesGBF1

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0002263 cell activation involved in immune response
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 Golgi apparatus
GO:0005801 cis-Golgi network
GO:0005802 trans-Golgi network
GO:0005811 lipid droplet
GO:0005829 cytosol
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO:0006892 post-Golgi vesicle-mediated transport
GO:0006895 Golgi to endosome transport
GO:0007030 Golgi organization
GO:0007346 regulation of mitotic cell cycle
GO:0015031 protein transport
GO:0016020 membrane
GO:0016032 viral process
GO:0030593 neutrophil chemotaxis
GO:0031252 cell leading edge
GO:0032012 regulation of ARF protein signal transduction
GO:0034067 protein localization to Golgi apparatus
GO:0042147 retrograde transport, endosome to Golgi
GO:0048205 COPI coating of Golgi vesicle
GO:0060271 cilium assembly
GO:0061162 establishment of monopolar cell polarity
GO:0070973 protein localization to endoplasmic reticulum exit site
GO:0080025 phosphatidylinositol-3,5-bisphosphate binding
GO:0090166 Golgi disassembly
GO:0097111 endoplasmic reticulum-Golgi intermediate compartment organization
GO:0098586 cellular response to virus
GO:1903409 reactive oxygen species biosynthetic process
GO:1903420 protein localization to endoplasmic reticulum tubular network
GO:2000008 regulation of protein localization to cell surface

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum-Golgi intermediate compartment
Golgi apparatus
Lipid droplet
Membrane

Domains

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DomainNameCategoryType
IPR000904 Sec7 domainDomainDomain
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR023394 Sec7, C-terminal domain superfamilyFamilyHomologous superfamily
IPR032691 Guanine nucleotide exchange factor, N-terminalDomainDomain
IPR035999 Sec7 domain superfamilyFamilyHomologous superfamily

Diseases

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