Entity Details

Primary name NGN1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92886
EntryNameNGN1_HUMAN
FullNameNeurogenin-1
TaxID9606
Evidenceevidence at protein level
Length237
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesNEUROG1

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007356 thorax and anterior abdomen determination
GO:0007399 nervous system development
GO:0021559 trigeminal nerve development
GO:0021650 vestibulocochlear nerve formation
GO:0030182 neuron differentiation
GO:0030432 peristalsis
GO:0031223 auditory behavior
GO:0031536 positive regulation of exit from mitosis
GO:0035112 genitalia morphogenesis
GO:0042472 inner ear morphogenesis
GO:0042803 protein homodimerization activity
GO:0043204 perikaryon
GO:0045165 cell fate commitment
GO:0045666 positive regulation of neuron differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048634 regulation of muscle organ development
GO:0048806 genitalia development
GO:0048839 inner ear development
GO:0050885 neuromuscular process controlling balance
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0070888 E-box binding
GO:0071626 mastication
GO:0090102 cochlea development
GO:0090103 cochlea morphogenesis
GO:0097094 craniofacial suture morphogenesis
GO:0098583 learned vocalization behavior
GO:1901078 negative regulation of relaxation of muscle
GO:1905747 negative regulation of saliva secretion
GO:1905748 hard palate morphogenesis
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR032653 Neurogenin-1FamilyFamily
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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