Entity Details

Primary name RIOK3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14730
EntryNameRIOK3_HUMAN
FullNameSerine/threonine-protein kinase RIO3
TaxID9606
Evidenceevidence at protein level
Length519
SequenceStatuscomplete
DateCreated2004-12-07
DateModified2021-06-02

Ontological Relatives

GenesRIOK3

GO terms

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GOName
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0007059 chromosome segregation
GO:0030490 maturation of SSU-rRNA
GO:0030688 preribosome, small subunit precursor
GO:0031333 negative regulation of protein-containing complex assembly
GO:0032728 positive regulation of interferon-beta production
GO:0039534 negative regulation of MDA-5 signaling pathway
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087 innate immune response
GO:0045089 positive regulation of innate immune response
GO:0046872 metal ion binding
GO:0051607 defense response to virus
GO:0071359 cellular response to dsRNA
GO:0089720 caspase binding
GO:0098586 cellular response to virus
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1990786 cellular response to dsDNA

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000687 RIO kinaseDomainDomain
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017406 Serine/threonine-protein kinase Rio3FamilyFamily
IPR018935 RIO kinase, conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB12010 FostamatinibDrugbanksmall molecule