Entity Details

Primary name UB2L6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14933
EntryNameUB2L6_HUMAN
FullNameUbiquitin/ISG15-conjugating enzyme E2 L6
TaxID9606
Evidenceevidence at protein level
Length153
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesUBE2L6

GO terms

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GOName
GO:0000151 ubiquitin ligase complex
GO:0000209 protein polyubiquitination
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006464 cellular protein modification process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0019985 translesion synthesis
GO:0031625 ubiquitin protein ligase binding
GO:0032020 ISG15-protein conjugation
GO:0032480 negative regulation of type I interferon production
GO:0042296 ISG15 transferase activity
GO:0043130 ubiquitin binding
GO:0061631 ubiquitin conjugating enzyme activity
GO:1990000 amyloid fibril formation

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000608 Ubiquitin-conjugating enzyme E2DomainDomain
IPR016135 Ubiquitin-conjugating enzyme/RWD-likeFamilyHomologous superfamily
IPR023313 Ubiquitin-conjugating enzyme, active siteSiteActive site

Diseases

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Interactions

51 interactions

InteractorPartnerSourcesPublicationsLink
UB2L6_HUMANR144B_HUMANBioGRID, HPRD, IntAct, MINT16427630 19549727 19690564 details
UB2L6_HUMANNAMPT_HUMANMINT18486613 details
UB2L6_HUMANMUL1_HUMANBioGRID, IntAct19690564 details
UB2L6_HUMANM3K1_HUMANBioGRID, IntAct19690564 details
UB2L6_HUMANPJA2_HUMANBioGRID, IntAct19690564 details
UB2L6_HUMANRN122_HUMANBioGRID, IntAct19690564 details
UB2L6_HUMANRN150_HUMANBioGRID, IntAct19690564 details
UB2L6_HUMANRNF25_HUMANBioGRID, IntAct19690564 details
UB2L6_HUMANSNURF_HUMANIntAct19690564 details
UB2L6_HUMANTOPRS_HUMANBioGRID, IntAct19690564 details
UB2L6_HUMANARI2_HUMANBioGRID, IntAct19549727 22037423 25416956 31515488 32296183 details
UB2L6_HUMANRN125_HUMANBioGRID, IntAct19549727 32296183 details
UB2L6_HUMANHOIL1_HUMANBioGRID, IntAct19549727 25416956 32296183 details
UB2L6_HUMANR144A_HUMANBioGRID, IntAct11722579 19549727 details
UB2L6_HUMANDTX3_HUMANBioGRID, IntAct19549727 32296183 details
UB2L6_HUMANTRAF7_HUMANBioGRID, IntAct19549727 details
UB2L6_HUMANTRI27_HUMANBioGRID, IntAct19549727 details
UB2L6_HUMANCBLC_HUMANBioGRID, IntAct19549727 details
UB2L6_HUMANTRIM8_HUMANBioGRID, IntAct19549727 32296183 details
UB2L6_HUMANLONF1_HUMANBioGRID, IntAct19549727 25416956 32296183 details
UB2L6_HUMANGDIR1_HUMANBioGRID, MINT21900206 details
UB2L6_HUMANPRKN_HUMANBioGRID, HPRD, UniProt11078524 21694720 22271254 details
UB2L6_HUMANTRI62_HUMANBioGRID, IntAct32296183 details
UB2L6_HUMANRN216_HUMANBioGRID, HPRD, IntAct15107846 32296183 details
UB2L6_HUMANTRI18_HUMANBioGRID, IntAct32296183 details
UB2L6_HUMANGBB2_HUMANIntAct32814053 details
UB2L6_HUMANLITAF_HUMANIntAct32814053 details
UB2L6_HUMANRNF4_HUMANBioGRID19690564 details
UB2L6_HUMANRUNX1_HUMANBioGRID18073335 details
UB2L6_HUMANSIAH1_HUMANBioGRID18073335 details
UB2L6_HUMANFLT3_HUMANBioGRID20508617 details
UB2L6_HUMANMINT_HUMANBioGRID, HPRD16583136 details
UB2L6_HUMANARI1_HUMANBioGRID, HPRD10521492 22037423 details
UB2L6_HUMANUBE3A_HUMANBioGRID, HPRD10558980 17433363 9153201 details
UB2L6_HUMANUB2L6_HUMANBioGRID20061386 details
UB2L6_HUMANRBX1_HUMANBioGRID24828503 details
UB2L6_HUMANUBA6_HUMANBioGRID19250909 details
UB2L6_HUMANUBA7_HUMANBioGRID19250909 details
UB2L6_HUMANUBA1_HUMANBioGRID30097011 9153201 details
UB2L6_HUMANHERC5_HUMANBioGRID20308324 details
UB2L6_HUMANNED4L_HUMANBioGRID28972136 details
UB2L6_HUMANFLNB_HUMANMINT19270716 details
UB2L6_HUMANRN19B_HUMANBioGRID, IntAct16709802 details
UB2L6_HUMANBRE1B_HUMANBioGRID, HPRD12121982 details
UB2L6_HUMANRN19A_HUMANBioGRID, HPRD11237715 details
UB2L6_HUMANTRI25_HUMANBioGRID, HPRD12075357 details
UB2L6_HUMANTIM8A_HUMANBioGRID22037423 details
UB2L6_HUMANSIAH2_HUMANBioGRID, HPRD11786535 details
UB2L6_HUMANBIRC2_HUMANBioGRID12525502 details
UB2L6_HUMANXIAP_HUMANBioGRID12525502 details
UB2L6_HUMANTYK2_HUMANBioGRID24833526 details