Entity Details

Primary name AIFM3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96NN9
EntryNameAIFM3_HUMAN
FullNameApoptosis-inducing factor 3
TaxID9606
Evidenceevidence at protein level
Length605
SequenceStatuscomplete
DateCreated2006-10-31
DateModified2021-06-02

Ontological Relatives

GenesAIFM3

GO terms

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GOName
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0050660 flavin adenine dinucleotide binding
GO:0051537 2 iron, 2 sulfur cluster binding
GO:0097194 execution phase of apoptosis

Subcellular Location

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Subcellular Location
Mitochondrion

Domains

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DomainNameCategoryType
IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamilyFamilyHomologous superfamily
IPR017941 Rieske [2Fe-2S] iron-sulphur domainDomainDomain
IPR023753 FAD/NAD(P)-binding domainDomainDomain
IPR028202 Reductase, C-terminalDomainDomain
IPR036188 FAD/NAD(P)-binding domain superfamilyFamilyHomologous superfamily
IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
AIFM3_HUMANPRIO_HUMANBioGRID, IntAct18482256 details
AIFM3_HUMANAPRIO_HUMANBioGRID18482256 details
AIFM3_HUMANA4_HUMANBioGRID21244100 21832049 details