Entity Details

Primary name HHIP_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96QV1
EntryNameHHIP_HUMAN
FullNameHedgehog-interacting protein
TaxID9606
Evidenceevidence at protein level
Length700
SequenceStatuscomplete
DateCreated2005-04-12
DateModified2021-06-02

Ontological Relatives

GenesHHIP

GO terms

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GOName
GO:0003824 catalytic activity
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005887 integral component of plasma membrane
GO:0007165 signal transduction
GO:0007405 neuroblast proliferation
GO:0008270 zinc ion binding
GO:0009953 dorsal/ventral pattern formation
GO:0009968 negative regulation of signal transduction
GO:0009986 cell surface
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway
GO:0043066 negative regulation of apoptotic process
GO:0045879 negative regulation of smoothened signaling pathway
GO:0048705 skeletal system morphogenesis
GO:0060170 ciliary membrane
GO:0060441 epithelial tube branching involved in lung morphogenesis
GO:0097108 hedgehog family protein binding

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Secreted

Domains

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DomainNameCategoryType
IPR000742 EGF-like domainDomainDomain
IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenaseFamilyHomologous superfamily
IPR011042 Six-bladed beta-propeller, TolB-likeFamilyHomologous superfamily
IPR012938 Glucose/Sorbosone dehydrogenaseDomainDomain
IPR018143 Folate receptor-likeDomainDomain

Diseases

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Interactions

4 interactions