Entity Details

Primary name ATOH8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96SQ7
EntryNameATOH8_HUMAN
FullNameProtein atonal homolog 8
TaxID9606
Evidenceevidence at protein level
Length321
SequenceStatuscomplete
DateCreated2008-03-18
DateModified2021-06-02

Ontological Relatives

GenesATOH8

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001704 formation of primary germ layer
GO:0001937 negative regulation of endothelial cell proliferation
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0010595 positive regulation of endothelial cell migration
GO:0010629 negative regulation of gene expression
GO:0016607 nuclear speck
GO:0030182 neuron differentiation
GO:0035148 tube formation
GO:0045603 positive regulation of endothelial cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046983 protein dimerization activity
GO:0051450 myoblast proliferation
GO:0060395 SMAD protein signal transduction
GO:0070888 E-box binding
GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR032660 Protein atonal homologue 8FamilyFamily
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
ATOH8_HUMANCP3A5_HUMANBioGRID, IntAct21988832 details
ATOH8_HUMANPP2BB_HUMANUniProt26496921 details
ATOH8_HUMANPP2BC_HUMANUniProt26496921 details