Entity Details

Primary name CDX2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99626
EntryNameCDX2_HUMAN
FullNameHomeobox protein CDX-2
TaxID9606
Evidenceevidence at protein level
Length313
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesCDX2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000794 condensed nuclear chromosome
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001568 blood vessel development
GO:0001829 trophectodermal cell differentiation
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008284 positive regulation of cell population proliferation
GO:0008327 methyl-CpG binding
GO:0008333 endosome to lysosome transport
GO:0009887 animal organ morphogenesis
GO:0009948 anterior/posterior axis specification
GO:0014807 regulation of somitogenesis
GO:0017053 transcription repressor complex
GO:0030154 cell differentiation
GO:0035019 somatic stem cell population maintenance
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity
GO:0045597 positive regulation of cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0060575 intestinal epithelial cell differentiation
GO:0060711 labyrinthine layer development
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000047 Helix-turn-helix motifSiteConserved site
IPR001356 Homeobox domainDomainDomain
IPR006820 Caudal-like activation domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR020479 Homeobox domain, metazoaDomainDomain

Diseases

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