Entity Details

Primary name ARC1B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15143
EntryNameARC1B_HUMAN
FullNameActin-related protein 2/3 complex subunit 1B
TaxID9606
Evidenceevidence at protein level
Length372
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesARPC1B

GO terms

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GOName
GO:0003779 actin binding
GO:0005200 structural constituent of cytoskeleton
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005885 Arp2/3 protein complex
GO:0005925 focal adhesion
GO:0015629 actin cytoskeleton
GO:0032355 response to estradiol
GO:0034314 Arp2/3 complex-mediated actin nucleation
GO:0036284 tubulobulbar complex
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043627 response to estrogen
GO:0044877 protein-containing complex binding
GO:0048013 ephrin receptor signaling pathway
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR017383 Actin-related protein 2/3 complex subunit 1FamilyFamily
IPR030141 Actin-related protein 2/3 complex subunit 1BFamilyFamily
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB08235 N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamideDrugbanksmall molecule
DB08236 (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-oneDrugbanksmall molecule