Entity Details

Primary name PAPP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BXP8
EntryNamePAPP2_HUMAN
FullNamePappalysin-2
TaxID9606
Evidenceevidence at protein level
Length1791
SequenceStatuscomplete
DateCreated2004-12-07
DateModified2021-06-02

Ontological Relatives

GenesPAPPA2

GO terms

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GOName
GO:0001558 regulation of cell growth
GO:0005576 extracellular region
GO:0005829 cytosol
GO:0006508 proteolysis
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0009651 response to salt stress
GO:0016324 apical plasma membrane
GO:0044267 cellular protein metabolic process
GO:0060349 bone morphogenesis
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000436 Sushi/SCR/CCP domainDomainDomain
IPR000800 Notch domainDomainDomain
IPR006558 LamG-like jellyroll foldDomainDomain
IPR008754 Peptidase M43, pregnancy-associated plasma-ADomainDomain
IPR011936 Myxococcus cysteine-rich repeatRepeatRepeat
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR026918 Pappalysin-2FamilyFamily
IPR035976 Sushi/SCR/CCP superfamilyFamilyHomologous superfamily
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR043543 Pappalysin-1/2FamilyFamily

Diseases

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Interactions

5 interactions