Entity Details

Primary name CHIA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BZP6
EntryNameCHIA_HUMAN
FullNameAcidic mammalian chitinase
TaxID9606
Evidenceevidence at protein level
Length476
SequenceStatuscomplete
DateCreated2003-10-24
DateModified2021-06-02

Ontological Relatives

GenesCHIA

GO terms

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GOName
GO:0000272 polysaccharide catabolic process
GO:0002376 immune system process
GO:0002532 production of molecular mediator involved in inflammatory response
GO:0004568 chitinase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0006030 chitin metabolic process
GO:0006032 chitin catabolic process
GO:0006915 apoptotic process
GO:0008061 chitin binding
GO:0019900 kinase binding
GO:0032722 positive regulation of chemokine production
GO:0044245 polysaccharide digestion

Subcellular Location

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Subcellular Location
Cytoplasm
Secreted

Domains

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DomainNameCategoryType
IPR001223 Glycoside hydrolase family 18, catalytic domainDomainDomain
IPR001579 Glycosyl hydrolases family 18 (GH18) active siteSiteActive site
IPR002557 Chitin binding domainDomainDomain
IPR011583 Chitinase IIDomainDomain
IPR017853 Glycoside hydrolase superfamilyFamilyHomologous superfamily
IPR029070 Chitinase insertion domain superfamilyFamilyHomologous superfamily
IPR036508 Chitin binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
CHIA_HUMANRB8NL_HUMANBioGRID, IntAct32296183 details
CHIA_HUMANTBCD5_HUMANBioGRID, IntAct32296183 details
CHIA_HUMANCOX20_HUMANBioGRID, IntAct32296183 details
CHIA_HUMANEGFR_HUMANIntAct18824549 details