Entity Details

Primary name SEM6A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H2E6
EntryNameSEM6A_HUMAN
FullNameSemaphorin-6A
TaxID9606
Evidenceevidence at protein level
Length1030
SequenceStatuscomplete
DateCreated2003-04-11
DateModified2021-06-02

Ontological Relatives

GenesSEMA6A

GO terms

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GOName
GO:0001755 neural crest cell migration
GO:0005615 extracellular space
GO:0005887 integral component of plasma membrane
GO:0006915 apoptotic process
GO:0007010 cytoskeleton organization
GO:0007166 cell surface receptor signaling pathway
GO:0007399 nervous system development
GO:0007411 axon guidance
GO:0009887 animal organ morphogenesis
GO:0016021 integral component of membrane
GO:0016525 negative regulation of angiogenesis
GO:0030215 semaphorin receptor binding
GO:0030335 positive regulation of cell migration
GO:0030424 axon
GO:0035924 cellular response to vascular endothelial growth factor stimulus
GO:0045499 chemorepellent activity
GO:0048843 negative regulation of axon extension involved in axon guidance
GO:0050919 negative chemotaxis
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0071526 semaphorin-plexin signaling pathway
GO:0106089 negative regulation of cell adhesion involved in sprouting angiogenesis
GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway
GO:1903671 negative regulation of sprouting angiogenesis
GO:2001224 positive regulation of neuron migration

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001627 Sema domainDomainDomain
IPR002165 Plexin repeatRepeatRepeat
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR016201 PSI domainDomainDomain
IPR027231 SemaphorinFamilyFamily
IPR036352 Sema domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

7 interactions