Entity Details

Primary name CRLF2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9HC73
EntryNameCRLF2_HUMAN
FullNameCytokine receptor-like factor 2
TaxID9606
Evidenceevidence at protein level
Length371
SequenceStatuscomplete
DateCreated2003-11-07
DateModified2021-06-02

Ontological Relatives

GenesCRLF2

GO terms

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GOName
GO:0004896 cytokine receptor activity
GO:0004923 leukemia inhibitory factor receptor activity
GO:0005127 ciliary neurotrophic factor receptor binding
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0008284 positive regulation of cell population proliferation
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0019955 cytokine binding
GO:0032754 positive regulation of interleukin-5 production
GO:0033005 positive regulation of mast cell activation
GO:0038111 interleukin-7-mediated signaling pathway
GO:0038165 oncostatin-M-mediated signaling pathway
GO:0043235 receptor complex
GO:1904894 positive regulation of receptor signaling pathway via STAT

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR003961 Fibronectin type IIIDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions