Entity Details

Primary name CAN10_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9HC96
EntryNameCAN10_HUMAN
FullNameCalpain-10
TaxID9606
Evidenceevidence at protein level
Length672
SequenceStatuscomplete
DateCreated2002-05-27
DateModified2021-06-02

Ontological Relatives

GenesCAPN10

GO terms

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GOName
GO:0000149 SNARE binding
GO:0004198 calcium-dependent cysteine-type endopeptidase activity
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006508 proteolysis
GO:0006921 cellular component disassembly involved in execution phase of apoptosis
GO:0008092 cytoskeletal protein binding
GO:0031532 actin cytoskeleton reorganization
GO:0032024 positive regulation of insulin secretion
GO:0032388 positive regulation of intracellular transport
GO:0032869 cellular response to insulin stimulus
GO:0046326 positive regulation of glucose import
GO:0097050 type B pancreatic cell apoptotic process
GO:2000676 positive regulation of type B pancreatic cell apoptotic process

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000169 Cysteine peptidase, cysteine active siteSiteActive site
IPR001300 Peptidase C2, calpain, catalytic domainDomainDomain
IPR022682 Peptidase C2, calpain, large subunit, domain IIIDomainDomain
IPR022683 Peptidase C2, calpain, domain IIIDomainDomain
IPR022684 Peptidase C2, calpain familyFamilyFamily
IPR028791 Calpain-10FamilyFamily
IPR033883 Calpain subdomain IIIDomainDomain
IPR036213 Calpain large subunit, domain III superfamilyFamilyHomologous superfamily
IPR038765 Papain-like cysteine peptidase superfamilyFamilyHomologous superfamily

Diseases

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