Entity Details

Primary name B2L10_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9HD36
EntryNameB2L10_HUMAN
FullNameBcl-2-like protein 10
TaxID9606
Evidenceevidence at protein level
Length204
SequenceStatuscomplete
DateCreated2002-09-19
DateModified2021-06-02

Ontological Relatives

GenesBCL2L10

GO terms

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GOName
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007283 spermatogenesis
GO:0007292 female gamete generation
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
GO:0042803 protein homodimerization activity
GO:0043066 negative regulation of apoptotic process
GO:0044233 mitochondria-associated endoplasmic reticulum membrane
GO:0046982 protein heterodimerization activity
GO:0089720 caspase binding
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Endoplasmic reticulum
Mitochondrion
Nucleus membrane

Domains

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DomainNameCategoryType
IPR002475 Bcl2-likeFamilyFamily
IPR020717 Apoptosis regulator, Bcl-2, BH1 motif, conserved siteSiteConserved site
IPR020726 Apoptosis regulator, Bcl-2, BH2 motif, conserved siteSiteConserved site
IPR026298 Bcl-2 familyFamilyFamily
IPR036834 Bcl-2-like superfamilyFamilyHomologous superfamily

Diseases

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