Entity Details

Primary name IL1AP_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NPH3
EntryNameIL1AP_HUMAN
FullNameInterleukin-1 receptor accessory protein
TaxID9606
Evidenceevidence at protein level
Length570
SequenceStatuscomplete
DateCreated2003-08-22
DateModified2021-06-02

Ontological Relatives

GenesIL1RAP

GO terms

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GOName
GO:0002114 interleukin-33 receptor activity
GO:0004908 interleukin-1 receptor activity
GO:0005149 interleukin-1 receptor binding
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0016020 membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0032736 positive regulation of interleukin-13 production
GO:0032753 positive regulation of interleukin-4 production
GO:0032754 positive regulation of interleukin-5 production
GO:0032755 positive regulation of interleukin-6 production
GO:0038172 interleukin-33-mediated signaling pathway
GO:0045087 innate immune response
GO:0050135 NAD(P)+ nucleosidase activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051965 positive regulation of synapse assembly
GO:0061809 NAD+ nucleotidase, cyclic ADP-ribose generating
GO:0065003 protein-containing complex assembly
GO:0070498 interleukin-1-mediated signaling pathway
GO:0098978 glutamatergic synapse
GO:0099151 regulation of postsynaptic density assembly
GO:0099545 trans-synaptic signaling by trans-synaptic complex
GO:0099560 synaptic membrane adhesion
GO:1905606 regulation of presynapse assembly

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR000157 Toll/interleukin-1 receptor homology (TIR) domainDomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR004074 Interleukin-1 receptor type I/IIFamilyFamily
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015621 Interleukin-1 receptor familyFamilyFamily
IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR041416 IL-1Ra-like, immunoglobulin domainDomainDomain

Diseases

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