Entity Details

Primary name CP26B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NR63
EntryNameCP26B_HUMAN
FullNameCytochrome P450 26B1
TaxID9606
Evidenceevidence at protein level
Length512
SequenceStatuscomplete
DateCreated2002-01-23
DateModified2021-06-02

Ontological Relatives

GenesCYP26B1

GO terms

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GOName
GO:0001709 cell fate determination
GO:0001768 establishment of T cell polarity
GO:0001822 kidney development
GO:0001972 retinoic acid binding
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0006766 vitamin metabolic process
GO:0006805 xenobiotic metabolic process
GO:0006954 inflammatory response
GO:0007140 male meiotic nuclear division
GO:0007283 spermatogenesis
GO:0008401 retinoic acid 4-hydroxylase activity
GO:0009954 proximal/distal pattern formation
GO:0010628 positive regulation of gene expression
GO:0016125 sterol metabolic process
GO:0016491 oxidoreductase activity
GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0020037 heme binding
GO:0030326 embryonic limb morphogenesis
GO:0033189 response to vitamin A
GO:0034653 retinoic acid catabolic process
GO:0042573 retinoic acid metabolic process
GO:0043587 tongue morphogenesis
GO:0045580 regulation of T cell differentiation
GO:0048384 retinoic acid receptor signaling pathway
GO:0048387 negative regulation of retinoic acid receptor signaling pathway
GO:0060349 bone morphogenesis
GO:0061436 establishment of skin barrier
GO:0070268 cornification
GO:0071300 cellular response to retinoic acid
GO:2001037 positive regulation of tongue muscle cell differentiation

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Microsome membrane

Domains

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DomainNameCategoryType
IPR001128 Cytochrome P450FamilyFamily
IPR002403 Cytochrome P450, E-class, group IVFamilyFamily
IPR017972 Cytochrome P450, conserved siteSiteConserved site
IPR036396 Cytochrome P450 superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00755 TretinoinDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CP26B_HUMANJPH3_HUMANIntAct32814053 details
CP26B_HUMANNED4L_HUMANBioGRID19953087 details