Entity Details

Primary name EFS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43281
EntryNameEFS_HUMAN
FullNameEmbryonal Fyn-associated substrate
TaxID9606
Evidenceevidence at protein level
Length561
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesEFS

GO terms

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GOName
GO:0005737 cytoplasm
GO:0005925 focal adhesion
GO:0007155 cell adhesion
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0016477 cell migration
GO:0017124 SH3 domain binding
GO:0019904 protein domain specific binding
GO:0035556 intracellular signal transduction
GO:0090527 actin filament reorganization

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR021901 CAS family, C-terminalDomainDomain
IPR035747 Embryonal Fyn-associated substrate, SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR037362 CAS familyFamilyFamily

Diseases

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Interactions

39 interactions

InteractorPartnerSourcesPublicationsLink
EFS_HUMANBCAR1_HUMANBioGRID, HPRD, IntAct16169070 details
EFS_HUMANSH2D3_HUMANBioGRID, HPRD, IntAct16189514 31515488 details
EFS_HUMANTPC6A_HUMANBioGRID, HPRD, IntAct16189514 32296183 details
EFS_HUMANVINEX_HUMANBioGRID, HPRD, IntAct16189514 details
EFS_HUMANABL1_HUMANIntAct17474147 details
EFS_HUMANCRK_HUMANBioGRID, IntAct17474147 8647432 details
EFS_HUMANSRC_HUMANBioGRID, IntAct17474147 8647432 details
EFS_HUMANGRB2_HUMANIntAct17474147 details
EFS_HUMANNCK1_HUMANBioGRID, IntAct17474147 26871637 details
EFS_HUMANP85A_HUMANIntAct17474147 details
EFS_HUMANPLCG1_HUMANIntAct17474147 details
EFS_HUMANNU155_HUMANBioGRID, IntAct25416956 details
EFS_HUMANSRBS2_HUMANBioGRID, IntAct25416956 32296183 details
EFS_HUMANFYN_HUMANBioGRID, IntAct12471123 25416956 31515488 32296183 details
EFS_HUMANBLK_HUMANBioGRID, IntAct25416956 29892012 31515488 32296183 details
EFS_HUMANZN417_HUMANBioGRID, IntAct25416956 details
EFS_HUMANOSTF1_HUMANBioGRID, IntAct25416956 32296183 details
EFS_HUMANTSSK1_HUMANBioGRID, IntAct25416956 32296183 details
EFS_HUMANABI2_HUMANBioGRID, IntAct25416956 29892012 31515488 32296183 details
EFS_HUMANNPAS2_HUMANBioGRID, IntAct24722188 details
EFS_HUMANLHX8_HUMANBioGRID, IntAct32296183 details
EFS_HUMANSPYA_HUMANBioGRID, IntAct32296183 details
EFS_HUMANYES_HUMANBioGRID, IntAct32296183 details
EFS_HUMANUBS3B_HUMANBioGRID, IntAct32296183 details
EFS_HUMANMYOZ3_HUMANBioGRID, IntAct32296183 details
EFS_HUMANGPAN1_HUMANBioGRID, IntAct32296183 details
EFS_HUMANPIN1_HUMANBioGRID, IntAct32296183 details
EFS_HUMANGLMN_HUMANBioGRID, IntAct32296183 details
EFS_HUMANSH3R2_HUMANBioGRID, IntAct32296183 details
EFS_HUMANNLGN3_HUMANBioGRID, IntAct25464930 details
EFS_HUMANBKRB2_HUMANBioGRID, MINT28298427 details
EFS_HUMANNCK2_HUMANBioGRID, IntAct26871637 31515488 details
EFS_HUMANPTN12_HUMANBioGRID, HPRD9748319 details
EFS_HUMANLYST_HUMANBioGRID11984006 details
EFS_HUMANA4_HUMANBioGRID21832049 details
EFS_HUMANUBC_HUMANBioGRID23314748 details
EFS_HUMANCC187_HUMANBioGRID32296183 details
EFS_HUMANNF1_HUMANMINT21653829 details
EFS_HUMANFAK2_HUMANHPRD9750131 details