Entity Details

Primary name NSMA3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NXE4
EntryNameNSMA3_HUMAN
FullNameSphingomyelin phosphodiesterase 4
TaxID9606
Evidenceevidence at protein level
Length866
SequenceStatuscomplete
DateCreated2007-01-23
DateModified2021-06-02

Ontological Relatives

GenesSMPD4

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0004767 sphingomyelin phosphodiesterase activity
GO:0005635 nuclear envelope
GO:0005640 nuclear outer membrane
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0006685 sphingomyelin catabolic process
GO:0006687 glycosphingolipid metabolic process
GO:0007029 endoplasmic reticulum organization
GO:0016021 integral component of membrane
GO:0042383 sarcolemma
GO:0046475 glycerophospholipid catabolic process
GO:0046513 ceramide biosynthetic process
GO:0046872 metal ion binding
GO:0050290 sphingomyelin phosphodiesterase D activity
GO:0071356 cellular response to tumor necrosis factor

Subcellular Location

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Subcellular Location
Cell membrane
Endoplasmic reticulum membrane
Golgi apparatus membrane
Nucleus envelope

Domains

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DomainNameCategoryType
IPR024129 Sphingomyelin phosphodiesterase 4FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00144 Phosphatidyl serineDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
NSMA3_HUMANEXOS4_HUMANBioGRID, HPRD, IntAct15231747 details
NSMA3_HUMANERBB2_HUMANBioGRID, IntAct31980649 details
NSMA3_HUMANST7_HUMANBioGRID29395067 details