Entity Details

Primary name CELR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NYQ6
EntryNameCELR1_HUMAN
FullNameCadherin EGF LAG seven-pass G-type receptor 1
TaxID9606
Evidenceevidence at protein level
Length3014
SequenceStatuscomplete
DateCreated2002-08-02
DateModified2021-06-02

Ontological Relatives

GenesCELSR1

GO terms

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GOName
GO:0001736 establishment of planar polarity
GO:0001764 neuron migration
GO:0001843 neural tube closure
GO:0004930 G protein-coupled receptor activity
GO:0005509 calcium ion binding
GO:0005654 nucleoplasm
GO:0005886 plasma membrane
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007266 Rho protein signal transduction
GO:0007417 central nervous system development
GO:0016021 integral component of membrane
GO:0032956 regulation of actin cytoskeleton organization
GO:0042249 establishment of planar polarity of embryonic epithelium
GO:0045176 apical protein localization
GO:0048105 establishment of body hair planar orientation
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis
GO:0060489 planar dichotomous subdivision of terminal units involved in lung branching morphogenesis
GO:0060490 lateral sprouting involved in lung morphogenesis
GO:0090251 protein localization involved in establishment of planar polarity
GO:0098609 cell-cell adhesion

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000203 GPS motifDomainDomain
IPR000742 EGF-like domainDomainDomain
IPR000832 GPCR, family 2, secretin-likeFamilyFamily
IPR001791 Laminin G domainDomainDomain
IPR001879 GPCR, family 2, extracellular hormone receptor domainDomainDomain
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR002049 Laminin EGF domainDomainDomain
IPR002126 Cadherin-likeDomainDomain
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR015919 Cadherin-like superfamilyFamilyHomologous superfamily
IPR017981 GPCR, family 2-likeDomainDomain
IPR020894 Cadherin conserved siteSiteConserved site
IPR032471 GAIN domain, N-terminalDomainDomain
IPR036445 GPCR family 2, extracellular hormone receptor domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CELR1_HUMANSAP_HUMANBioGRID, HPRD, IntAct16169070 details