Entity Details

Primary name KCNQ2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43526
EntryNameKCNQ2_HUMAN
FullNamePotassium voltage-gated channel subfamily KQT member 2
TaxID9606
Evidenceevidence at protein level
Length872
SequenceStatuscomplete
DateCreated2001-06-01
DateModified2021-06-02

Ontological Relatives

GenesKCNQ2

GO terms

Show/Hide Table
GOName
GO:0005249 voltage-gated potassium channel activity
GO:0005251 delayed rectifier potassium channel activity
GO:0005516 calmodulin binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007268 chemical synaptic transmission
GO:0007399 nervous system development
GO:0008076 voltage-gated potassium channel complex
GO:0016021 integral component of membrane
GO:0030506 ankyrin binding
GO:0033268 node of Ranvier
GO:0034765 regulation of ion transmembrane transport
GO:0043194 axon initial segment
GO:0045202 synapse
GO:0071805 potassium ion transmembrane transport

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR003937 Potassium channel, voltage dependent, KCNQFamilyFamily
IPR003947 Potassium channel, voltage dependent, KCNQ2FamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR013821 Potassium channel, voltage dependent, KCNQ, C-terminalDomainDomain
IPR020969 Ankyrin-G binding siteSiteBinding site
IPR028325 Voltage-gated potassium channelFamilyFamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB00228 EnfluraneDrugbanksmall molecule
DB00321 AmitriptylineDrugbanksmall molecule
DB00586 DiclofenacDrugbanksmall molecule
DB00939 Meclofenamic acidDrugbanksmall molecule
DB01069 PromethazineDrugbanksmall molecule
DB01110 MiconazoleDrugbanksmall molecule
DB04953 EzogabineDrugbanksmall molecule
DB06089 ICA-105665Drugbanksmall molecule