Entity Details

Primary name ATS1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UHI8
EntryNameATS1_HUMAN
FullNameA disintegrin and metalloproteinase with thrombospondin motifs 1
TaxID9606
Evidenceevidence at protein level
Length967
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesADAMTS1

GO terms

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GOName
GO:0001542 ovulation from ovarian follicle
GO:0001822 kidney development
GO:0004222 metalloendopeptidase activity
GO:0005576 extracellular region
GO:0005604 basement membrane
GO:0007229 integrin-mediated signaling pathway
GO:0008201 heparin binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0008285 negative regulation of cell population proliferation
GO:0016525 negative regulation of angiogenesis
GO:0030198 extracellular matrix organization
GO:0031012 extracellular matrix
GO:0031410 cytoplasmic vesicle
GO:0060347 heart trabecula formation
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation
GO:1904754 positive regulation of vascular associated smooth muscle cell migration

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000884 Thrombospondin type-1 (TSP1) repeatRepeatRepeat
IPR001590 Peptidase M12B, ADAM/reprolysinDomainDomain
IPR002870 Peptidase M12B, propeptideDomainDomain
IPR006586 ADAM, cysteine-rich domainDomainDomain
IPR010294 ADAM-TS Spacer 1DomainDomain
IPR013273 ADAMTS/ADAMTS-likeFamilyFamily
IPR013274 Peptidase M12B, ADAM-TS1FamilyFamily
IPR024079 Metallopeptidase, catalytic domain superfamilyFamilyHomologous superfamily
IPR036383 Thrombospondin type-1 (TSP1) repeat superfamilyFamilyHomologous superfamily
IPR041645 ADAM cysteine-rich domain 2DomainDomain

Diseases

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