Entity Details

Primary name ATS7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UKP4
EntryNameATS7_HUMAN
FullNameA disintegrin and metalloproteinase with thrombospondin motifs 7
TaxID9606
Evidenceevidence at protein level
Length1686
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesADAMTS7

GO terms

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GOName
GO:0004222 metalloendopeptidase activity
GO:0005576 extracellular region
GO:0005788 endoplasmic reticulum lumen
GO:0008237 metallopeptidase activity
GO:0030198 extracellular matrix organization
GO:0031012 extracellular matrix
GO:0032331 negative regulation of chondrocyte differentiation
GO:0046872 metal ion binding
GO:0051603 proteolysis involved in cellular protein catabolic process
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor
GO:0071773 cellular response to BMP stimulus

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000884 Thrombospondin type-1 (TSP1) repeatRepeatRepeat
IPR001590 Peptidase M12B, ADAM/reprolysinDomainDomain
IPR002870 Peptidase M12B, propeptideDomainDomain
IPR010294 ADAM-TS Spacer 1DomainDomain
IPR010909 PLACDomainDomain
IPR013273 ADAMTS/ADAMTS-likeFamilyFamily
IPR024079 Metallopeptidase, catalytic domain superfamilyFamilyHomologous superfamily
IPR036383 Thrombospondin type-1 (TSP1) repeat superfamilyFamilyHomologous superfamily
IPR041645 ADAM cysteine-rich domain 2DomainDomain

Diseases

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Interactions

3 interactions