Entity Details

Primary name ACINU_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UKV3
EntryNameACINU_HUMAN
FullNameApoptotic chromatin condensation inducer in the nucleus
TaxID9606
Evidenceevidence at protein level
Length1341
SequenceStatuscomplete
DateCreated2003-02-28
DateModified2021-06-02

Ontological Relatives

GenesACIN1

GO terms

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GOName
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0016607 nuclear speck
GO:0016887 ATP hydrolysis activity
GO:0019899 enzyme binding
GO:0030218 erythrocyte differentiation
GO:0030263 apoptotic chromosome condensation
GO:0043065 positive regulation of apoptotic process
GO:0045657 positive regulation of monocyte differentiation
GO:0048025 negative regulation of mRNA splicing, via spliceosome
GO:0061574 ASAP complex

Subcellular Location

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Subcellular Location
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR003034 SAP domainDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR032552 Acin1, RNSP1-SAP18 binding (RSB) motifSiteConserved site
IPR034257 Acinus, RNA recognition motifDomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily
IPR036361 SAP domain superfamilyFamilyHomologous superfamily

Diseases

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