Entity Details

Primary name EPCR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UNN8
EntryNameEPCR_HUMAN
FullNameEndothelial protein C receptor
TaxID9606
Evidenceevidence at protein level
Length238
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesPROCR

GO terms

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GOName
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005813 centrosome
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005925 focal adhesion
GO:0007596 blood coagulation
GO:0009986 cell surface
GO:0038023 signaling receptor activity
GO:0048471 perinuclear region of cytoplasm
GO:0050819 negative regulation of coagulation
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR011161 MHC class I-like antigen recognition-likeDomainDomain
IPR011162 MHC classes I/II-like antigen recognition proteinFamilyHomologous superfamily
IPR015669 Endothelial protein C receptorFamilyFamily
IPR037055 MHC class I-like antigen recognition-like superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00055 Drotrecogin alfaDrugbankbiotech
DB04327 PhosphatidylethanolamineDrugbanksmall molecule
DB11328 Tetradecyl hydrogen sulfate (ester)Drugbanksmall molecule

Interactions

6 interactions