Entity Details

Primary name AURKC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UQB9
EntryNameAURKC_HUMAN
FullNameAurora kinase C
TaxID9606
Evidenceevidence at protein level
Length309
SequenceStatuscomplete
DateCreated2003-01-17
DateModified2021-06-02

Ontological Relatives

GenesAURKC

GO terms

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GOName
GO:0000775 chromosome, centromeric region
GO:0000793 condensed chromosome
GO:0004672 protein kinase activity
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005876 spindle microtubule
GO:0006468 protein phosphorylation
GO:0007052 mitotic spindle organization
GO:0007283 spermatogenesis
GO:0008608 attachment of spindle microtubules to kinetochore
GO:0016570 histone modification
GO:0030496 midbody
GO:0031616 spindle pole centrosome
GO:0032133 chromosome passenger complex
GO:0032465 regulation of cytokinesis
GO:0032467 positive regulation of cytokinesis
GO:0035174 histone serine kinase activity
GO:0048599 oocyte development
GO:0051233 spindle midzone
GO:0051256 mitotic spindle midzone assembly
GO:0051301 cell division
GO:0051321 meiotic cell cycle
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR030613 Aurora kinase CFamilyFamily
IPR030616 Aurora kinaseFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB06134 SNS-314Drugbanksmall molecule
DB12010 FostamatinibDrugbanksmall molecule