Entity Details

Primary name S4A4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y6R1
EntryNameS4A4_HUMAN
FullNameElectrogenic sodium bicarbonate cotransporter 1
TaxID9606
Evidenceevidence at protein level
Length1079
SequenceStatuscomplete
DateCreated2005-12-20
DateModified2021-06-02

Ontological Relatives

GenesSLC4A4

GO terms

Show/Hide Table
GOName
GO:0005452 inorganic anion exchanger activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006814 sodium ion transport
GO:0008510 sodium:bicarbonate symporter activity
GO:0009986 cell surface
GO:0015293 symporter activity
GO:0015701 bicarbonate transport
GO:0016020 membrane
GO:0016323 basolateral plasma membrane
GO:0022857 transmembrane transporter activity
GO:0035725 sodium ion transmembrane transport
GO:0036376 sodium ion export across plasma membrane
GO:0042391 regulation of membrane potential
GO:0042802 identical protein binding
GO:0045821 positive regulation of glycolytic process
GO:0050801 ion homeostasis
GO:0051453 regulation of intracellular pH
GO:0055085 transmembrane transport
GO:0070062 extracellular exosome
GO:0150104 transport across blood-brain barrier

Subcellular Location

Show/Hide Table
Subcellular Location
Basolateral cell membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR003020 Bicarbonate transporter, eukaryoticFamilyFamily
IPR003024 Sodium bicarbonate cotransporterFamilyFamily
IPR011531 Bicarbonate transporter, C-terminalDomainDomain
IPR013769 Band 3 cytoplasmic domainDomainDomain
IPR016152 Phosphotransferase/anion transporterFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB01390 Sodium bicarbonateSwissprotsmall molecule

Interactions

4 interactions